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Editorial: Improving the Way Science is Done, Evaluated, and Published

Phase IIA trial testing erlotinib as an intervention against intraductal pancreatic mucinous neoplasms.

Intraductal papillary mucinous neoplasms (IPMN) are a distinct type of precursor lesions that cause about 5% of pancreatic adenocarcinoma (1, 2). Four-year survival rates of 40% to 75% are reported (3-7). There is currently no chemotherapy specifically approved for treating IPMNs. The number of IPMN cases has significantly increased over the last decade (8).

Ergonomics in the formation of work condition quality.

The specific organizing the conditions of executing the job makes up the essential decisive about possibility obtainment element of competitive superiority. The ergonomic requirements are essential element of this process. They unite the environment of work with principles of the SCR, causing enlargement the man's part in development of enterprise.

On Slater's condition and finite convergence of the Douglas-Rachford algorithm for solving convex feasibility problems in Euclidean spaces

The Douglas–Rachford algorithm is a classical and very successful method for solving optimization and feasibility problems. In this paper, we provide novel conditions sufficient for finite convergence in the context of convex feasibility problems. Our analysis builds upon, and considerably extends, pioneering work by Spingarn. Specifically, we obtain finite convergence in the presence of Slater...

On the impact of the distance between two genes on their interaction curve.

We analyze a basic building block of gene regulatory networks using a stochastic/geometric model in search of a mathematical backing for the discrete modeling frameworks. We consider a network consisting only of two interacting genes: a source gene and a target gene. The target gene is activated by the proteins encoded by the source gene. The interaction is therefore mediated by activator prote...